Beclin 1 (BECN1) Mouse Monoclonal Antibody [Clone ID: OTI4A10]

CAT#: CF502617

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Carrier-free (BSA/glycerol-free) BECN1 mouse monoclonal antibody, clone OTI4A10 (formerly 4A10)



USD 600.00


Availability*
In Stock

Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI4A10
Applications FC, IF, WB
Recommended Dilution WB 1:2000, IF 1:100, FLOW 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BECN1 (NP_003757) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 51.7 kDa
Gene Name Homo sapiens beclin 1 (BECN1), transcript variant 1, mRNA.
Background Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]). [supplied by OMIM, Jul 2010]
Synonyms ATG6; beclin1; VPS30
Reference Data
Protein Families Druggable Genome
Protein Pathways Regulation of autophagy
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