HDAC6 Mouse Monoclonal Antibody [Clone ID: OTI3E7]

CAT#: CF502177

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Carrier-free (BSA/glycerol-free) HDAC6 mouse monoclonal antibody, clone OTI3E7 (formerly 3E7)



  View other "OTI3E7" antibodies (4)

USD 545.00


Availability*
In Stock

Size
    • 100 ug


Specifications

Product Data
Clone Name OTI3E7
Applications FC, IHC, WB
Recommended Dilution WB 1:500~1000, IHC 1:150, FLOW 1:100
Reactivity Human, Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 131.2 kDa
Gene Name Homo sapiens histone deacetylase 6 (HDAC6), transcript variant 5, mRNA.
Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq]
Synonyms CPBHM; HD6; JM21; PPP1R90
Reference Data
Protein Families Druggable Genome, Transcription Factors

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