Ribonuclease Inhibitor (RNH1) Mouse Monoclonal Antibody [Clone ID: OTI3F11]

SKU CF501875

Carrier-free (BSA/glycerol-free) RNH1 mouse monoclonal antibody, clone OTI3F11 (formerly 3F11)

Product Data

• Clone Name: OTI3F11
• Application: FC, IHC, WB
• Recommended Dilution: WB 1:500~2000, FLOW 1:100, IHC: 1:150
• Reactivity: Dog, Human, Monkey, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human RNH1 (NP_002930) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 49.8 kDa
• Gene Name: ribonuclease/angiogenin inhibitor 1
• Database Link:
  NP_002930
  P13489
• Background: Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo. [supplied by OMIM]
• Synonyms: RAI; RNH

Reference Data