PIK3AP1 Mouse Monoclonal Antibody [Clone ID: OTI5A1]

SKU CF501722

Carrier-free (BSA/glycerol-free) PIK3AP1 mouse monoclonal antibody, clone OTI5A1 (formerly 5A1)

Product Data

• Clone Name: OTI5A1
• Application: FC, IF, WB
• Recommended Dilution: WB 1:2000, IF 1:100, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human PIK3AP1 (NP_689552) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 90.2 kDa
• Gene Name: phosphoinositide-3-kinase adaptor protein 1
• Database Link:
  NP_689522
  Q6ZUJ8
• Background: Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).
• Synonyms: BCAP

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: B cell receptor signaling pathway