BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: OTI10B7]

CAT#: CF500535

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Carrier-free (BSA/glycerol-free) BUB1B mouse monoclonal antibody, clone OTI10B7 (formerly 10B7)



  View other "OTI10B7" antibodies (4)

USD 545.00


Availability*
4 Weeks

Size
    • 100 ug


Specifications

Product Data
Clone Name OTI10B7
Applications IF, IHC, WB
Recommended Dilution WB 1:2000 IHC 1:50 IF 1:100
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human BUB1B expression vector
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 119.5 kDa
Gene Name Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), mRNA.
Background This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Synonyms Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1
Reference Data
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways Cell cycle

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.