BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: OTI10B7]
SKU
CF500535
Carrier-free (BSA/glycerol-free) BUB1B mouse monoclonal antibody, clone OTI10B7 (formerly 10B7)
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TrueMAB™
Antibodies made against full-length proteins as antigens.
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Product Data | |
Clone Name | OTI10B7 |
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Application | IF, IHC, WB |
Recommended Dilution | WB 1:2000 IHC 1:50 IF 1:100 |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full-length protein expressed in 293T cell transfected with human BUB1B expression vector |
Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Ambient |
Predicted Protein Size | 119.5 kDa |
Gene Name | BUB1 mitotic checkpoint serine/threonine kinase B |
Database Link | |
Background | This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. |
Synonyms | Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
Protein Pathways | Cell cycle |
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Product Manuals |
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Antibody Resources |
SKU | Description | Size | Price | |
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TA500535 | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI10B7 (formerly 10B7) | 100 ul |
$447.00
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TA500535AM | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI10B7 (formerly 10B7), Biotinylated | 100 ul |
$509.00
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TA500535BM | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI10B7 (formerly 10B7), HRP conjugated | 100 ul |
$509.00
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TA500535S | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI10B7 (formerly 10B7) | 30 ul |
$200.00
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.