Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: OTI2E4]

CAT#: CF500022

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Carrier-free (BSA/glycerol-free) CK8 mouse monoclonal antibody, clone OTI2E4 (formerly 2E4)



  View other "OTI2E4" antibodies (4)

USD 600.00


Availability*
4 Weeks

Size
    • 100 ug


Other products for "KRT8"

Specifications

Product Data
Clone Name OTI2E4
Applications IF, IHC, WB
Recommended Dilution WB 1:500~1000, IHC 1:50, IF 1:50~100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 53.5 kDa
Gene Name Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.
Background Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Reference Data
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.