Cytokeratin 8 (KRT8) (+ KRT18) Guinea Pig Polyclonal Antibody

CAT#: BP5007

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Cytokeratin 8 (KRT8) (+ KRT18) guinea pig polyclonal antibody, Serum



USD 495.00


Availability*
2 Weeks

Size
    • 100 ul


Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution ELISA.
Immunoblotting: 1/2000 for Western blotting.
Cytological material.
Immunohistochemistry on Frozen Tissue: 1/100.
Immunohistochemistry on Paraffin-Embedded Tissue: 1/50 (microwave treatment recommended).
Incubation Time: 1 h at RT, extended with Paraffin.
Reactivities Bovine, Chicken, Hamster, Human, Mouse, Rat, Xenopus
Host Guinea Pig
Clonality Polyclonal
Immunogen Keratin K8/K18 filaments, reconstituted from purified Bovine keratins K8 and K18
Specificity Reactive Polypeptide: Mr 52 500 and 45 500 Keratins K8 and K18 of simple type epithelium.
Tumors Specifically Detected: All adenocarcinoma tested, undifferentiated carcinoma, hepatocellular carcinoma, cervix carcinoma.
Formulation State: Serum
State: Liquid stabilized antiserum
Preservative: 0.09% Sodium Azide
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens keratin 8 (KRT8), transcript variant 2
Background Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.
Synonyms KRT8, CYK8, Cytokeratin-8, CK8, Keratin-8, K8, Cytokeratin endo A
Reference Data
Protein Families Druggable Genome
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