KEL Mouse Monoclonal Antibody [Clone ID: BRIC203]

CAT#: BM259P

KEL mouse monoclonal antibody, clone BRIC203, Purified

Specifications

Product Data

• Clone Name: BRIC203
• Applications: AGG, ELISA, IHC
• Recommended Dilution: Immunoprecipitation.
  Haemagglutination.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human Erythrocytes.
  Spleen cells from immunised Balb/c were fused with cells of a myeloma cell line.
• Specificity: This antibody recognises CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on a 93kD erythrocyte membrane glycoprotein.
  In haemaggulation tests, BRIC203 reacts with Kp (a-b+) but not Kp (a+b-).
  In addition this antibody will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko Erythrocytes.
• Formulation: Tris Buffered Glycine, pH 7.8 containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Kell blood group, metallo-endopeptidase
• Database Link:
  Entrez Gene 3792 Human
  UniProt ID P23276
• Background: Blood Group Kell Antigen is a type II transmembrane glycoprotein. The Kell glycoprotein links to the XK membrane protein, that carries the Kx antigen via a single disulfide bond. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
• Synonyms: Kell blood group glycoprotein