KEL Mouse Monoclonal Antibody [Clone ID: BRIC203]
| Product Data | |
| Clone Name | BRIC203 |
|---|---|
| Application | AGG, ELISA, IHC |
| Recommended Dilution | Immunoprecipitation. Haemagglutination. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human Erythrocytes. Spleen cells from immunised Balb/c were fused with cells of a myeloma cell line. |
| Specificity | This antibody recognises CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on a 93kD erythrocyte membrane glycoprotein. In haemaggulation tests, BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition this antibody will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko Erythrocytes. |
| Buffer | Tris Buffered Glycine, pH 7.8 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | Kell blood group, metallo-endopeptidase |
| Database Link | |
| Background | Blood Group Kell Antigen is a type II transmembrane glycoprotein. The Kell glycoprotein links to the XK membrane protein, that carries the Kx antigen via a single disulfide bond. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. |
| Synonyms | Kell blood group glycoprotein |
| Reference Data | |
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