ICAM1 Mouse Monoclonal Antibody [Clone ID: MEM-111]

CAT#: BM2448P

ICAM1 mouse monoclonal antibody, clone MEM-111, Purified


USD 244.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name MEM-111
Applications ELISA, FC, IHC, WB
Recommended Dilution Flow cytometry: Recommended dilution: 0.5-4 μg/ml.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml; positive tissue: thymus, RE cells.
Western blotting: Positive control: RAJI cell line K562 leukemia cell line, JY cell line, aa ctivated T-lymphocytes, non-reducing conditions.
Reactivities Human, Rat, Bovine
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Raji Human Burkitt's lymphoma cell line.
Specificity Clone MEM-111 reacts with CD54.
Formulation PBS, pH~7.4
State: Purified
State: Liquid purified Ig fraction (95% pure by SDS-PAGE)
Preservative: 15mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name intercellular adhesion molecule 1
Background ICAM-1 (MW 90 kD) is a member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells.
CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
Synonyms ICAM-1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.