ICAM1 Mouse Monoclonal Antibody [Clone ID: MEM-111]

CAT#: BM2448P

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ICAM1 mouse monoclonal antibody, clone MEM-111, Purified



USD 242.00


Availability*
2 Weeks

Size
    • 100 ug


Product images

Specifications

Product Data
Clone Name MEM-111
Applications ELISA, FC, IHC, WB
Recommended Dilution Immunohistochemistry on Paraffin Sections:
Recommended Dilution: 10 µg/ml.
Positive tissue: thymus, RE cells.
Flow Cytometry:
Recommended Dilution: 2 µg/ml.
ELISA.
Western blotting (Non-Reducing Conditions).
Positive Control: RAJI cell line, K562 leukemia cell line, JY cell line, Activated T-lymphocytes.
Reactivity Bovine, Human, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Raji Human Burkitt's lymphoma cell line.
Specificity Clone MEM-111 reacts with CD54.
Formulation PBS, pH~7.4
State: Purified
State: Liquid purified Ig fraction (95% pure by SDS-PAGE)
Preservative: 15mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name intercellular adhesion molecule 1
Background ICAM-1 (MW 90 kD) is a member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells.
CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
Synonyms ICAM-1
Reference Data
Other products for "ICAM1"
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