ICAM1 Mouse Monoclonal Antibody [Clone ID: MEM-111]
ICAM1 mouse monoclonal antibody, clone MEM-111, Purified
|Applications||ELISA, FC, IHC, WB|
|Recommended Dilution||Immunohistochemistry on Paraffin Sections:
Recommended Dilution: 10 µg/ml.
Positive tissue: thymus, RE cells.
Recommended Dilution: 2 µg/ml.
Western blotting (Non-Reducing Conditions).
Positive Control: RAJI cell line, K562 leukemia cell line, JY cell line, Activated T-lymphocytes.
|Reactivity||Bovine, Human, Rat|
|Immunogen||Raji Human Burkitt's lymphoma cell line.|
|Specificity||Clone MEM-111 reacts with CD54.|
State: Liquid purified Ig fraction (95% pure by SDS-PAGE)
Preservative: 15mM Sodium Azide
|Purification||Affinity Chromatography on Protein A|
|Storage||Store undiluted at 2-8°C.
DO NOT FREEZE!
|Stability||Shelf life: one year from despatch.|
|Gene Name||intercellular adhesion molecule 1|
|Background||ICAM-1 (MW 90 kD) is a member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells.
CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.