Semaphorin 7a (SEMA7A) Mouse Monoclonal Antibody [Clone ID: MEM-150]

SKU BM108S

Semaphorin 7a (SEMA7A) mouse monoclonal antibody, clone MEM-150, Purified

Product Data

• Clone Name: MEM-150
• Application: FC, IP, WB
• Recommended Dilution: Flow Cytometry: 4 µg/ml.; Immunoprecipitation.; Western Blot under non reducing conditions.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: HPB-ALL human T cell line
• Specificity: The antibody reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.
• Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4; State: Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Ion exchange chromatography; purity: > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: semaphorin 7A (John Milton Hagen blood group)
• Database Link:
  O75326
• Background: CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors plexin C1 and b1 integrins.
• Synonyms: Semaphorin-7A, SEMAL, Semaphorin-L, Semaphorin-K1

Reference Data