VEGF Receptor 1 (FLT1) pTyr1048 Rabbit Polyclonal Antibody
Product Data | |
Application | IHC |
---|---|
Recommended Dilution | Immunohistochemistry on paraffin sections: 1:50~1:100 . |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 1048 (D-I-Y(p)-K-N) derived from Human VEGFR1 (KLH-conjugated) |
Specificity | The antibody detects endogenous levels of VEGFR1 only when phosphorylated at tyrosine 1048. |
Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography using epitope-specific peptide |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 150 kDa |
Gene Name | fms related tyrosine kinase 1 |
Database Link | |
Background | Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis. |
Synonyms | VEGFR1, FLT1, FLT, FRT, VEGF Receptor 1 |
Reference Data |
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