SHANK2 (Center) Rabbit Polyclonal Antibody

SKU AP53906PU-N

SHANK2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/1000.

• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of Human SHANK2.
• Specificity: This antibody recognizes Mouse SHANK2 (Center).; Other species not tested.
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 158822 Da
• Gene Name: SH3 and multiple ankyrin repeat domains 2
• Database Link:
  Q9UPX8
• Background:
  This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq].
• Synonyms: Cortactin-binding protein 1, CORTBP1, PROSAP1, SPANK-3, SPANK3, KIAA1022

Reference Data