SCN1B (N-term) Rabbit Polyclonal Antibody

SKU AP53815PU-N

SCN1B (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1,000.; Western blotting: 1/100-1/500.; Flow Cytometry: 1/10-1/50.; Immunohistochemistry: 1/50-1/100.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of Human SCN1B
• Specificity: Recognizes SCN1B (N-Term).
• Buffer: PBS with 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: sodium voltage-gated channel beta subunit 1
• Database Link:
  Q07699
• Background: Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. SCN1B encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: GEFSP1
• Note: Molecular Weight: 24707 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Sodium, Transmembrane