Calcium independent Phospholipase A2 (PLA2G6) (Center) Rabbit Polyclonal Antibody

SKU AP53326PU-N

Calcium independent Phospholipase A2 (PLA2G6) (Center) rabbit polyclonal antibody, Purified

Product Data

• Application: FC, IF, IHC, WB
• Recommended Dilution:

  Flow cytometry: 1/10-1/50.; Immunofluorescence: 1/10-1/50.; Immunohistochemistry on Paraffin sections: 1/50-1/100.; Western blot: 1/50-1/100.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 558-588aa) of human PLA2G6.
• Specificity: This antibody recognizes PLA2G6.
• Buffer: PBS with 0.09% (W/V) Sodium azide; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: phospholipase A2 group VI
• Database Link:
  O60733
• Background: The protein encoded by the PLA2G6 gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells.
• Synonyms: IPLA2, Cal-PLA2, GVI PLA2, Group VI phospholipase A2, PARK14
• Note: Molecular Weight: 89903 Da

Reference Data

• Protein Pathways: alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway