PAICS (N-term) Rabbit Polyclonal Antibody

SKU AP53152PU-N

PAICS (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000. ; Western Blot: 1/100-1/500. ; Flow Cytometry: 1/10-1/50. ; Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 94-123 amino acids from the N-terminal region of human PAICS
• Specificity: This antibody recognizes Human and Mouse PAICS (N-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase
• Database Link:
  P22234
• Background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: PAIS, AIRC
• Note: Molecular Weight: 47079 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism