NUDT15 (C-term) Rabbit Polyclonal Antibody

SKU AP52959PU-N

NUDT15 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution:

  Flow cytometry: 1/10-1/50.; Immunohistochemistry on Paraffin sections: 1/50-1/100.; Western blot: 1/1000.; Enzyme immunoassay: 1/1000.

• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 89-118aa) of human NUDT15.
• Specificity: This antibody recognizes NUDT15.
• Buffer: PBS with 0.09% (W/V) Sodium azide; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: nudix hydrolase 15
• Database Link:
  Q9NV35
• Background: Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
• Synonyms: MTH2, MutT homolog 2, Nudix motif 15
• Note: Molecular Weight: 18609 Da

Reference Data