MTMR6 (N-term) Rabbit Polyclonal Antibody

CAT#: AP52768PU-N

MTMR6 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in HL-60 cell line lysates (35ug/lane) using MTMR6 antibody. (N-term). This demonstrates this antibody detected the MTMR6 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/1,000.
  Enzyme immunoassay: 1/1,000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of Human MTMR6.
• Specificity: This antibody recognizes Human MTMR6 at N-term.
  Other species not tested.
• Formulation: PBS with 0.09% (W/V) Sodium Azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens myotubularin related protein 6 (MTMR6)
• Database Link:
  Entrez Gene 9107 Human
  UniProt ID Q9Y217
• Background: Myotubularin-related protein 6 is a phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase and negatively regulates proliferation of reactivated CD4⁺ T-cells
• Synonyms: Myotubularin-related protein 6
• Note: Molecular Weight: 71954 Da

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism