HB EGF (HBEGF) (Center) Rabbit Polyclonal Antibody

SKU AP52008PU-N

HB EGF (HBEGF) (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1/1000. ; Western Blot: 1/100-1/500.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of Human HBEGF
• Specificity: This antibody recognizes Human HBEGF (Center).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: heparin binding EGF like growth factor
• Database Link:
  Q99075
• Background: HBEGF may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
• Synonyms: DTR, DTS, HEGFL
• Note: Molecular Weight: 23067 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway