Endothelin 1 (EDN1) (Center) Rabbit Polyclonal Antibody

SKU AP51364PU-N

Endothelin 1 (EDN1) (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IF, IHC, WB
• Recommended Dilution: ELISA: 1/1000.; Western Blot: 1/1000.; Flow Cytometry: 1/10-1/50. ; Immunofluorescence: 1/10-1/50. ; Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human EDN1
• Specificity: This antibody recognizes Human Endothelin-1 (Center).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: endothelin 1
• Database Link:
  P05305
• Background:
  The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: PPET1, EDN1, ET1, HDLCQ7, EDN1
• Note: Molecular Weight: 24425 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Melanogenesis