Dynein intermediate chain 1 (DNAI1) (N-term) Rabbit Polyclonal Antibody
SKU
AP51284PU-N
Dynein intermediate chain 1 (DNAI1) (N-term) rabbit polyclonal antibody, Aff - Purified
Product Data | |
Application | WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 91-120 amino acids from the N-terminal region of human DNAI1 |
Specificity | This antibody recognizes Human DNAI1 (N-term). |
Buffer | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | dynein axonemal intermediate chain 1 |
Database Link | |
Background | The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. |
Synonyms | Dynein intermediate chain 1 axonemal |
Note | Molecular Weight: 79283 Da |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Huntington's disease |
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