Corticotropin Releasing Factor Receptor 2 (CRHR2) Rabbit Polyclonal Antibody

SKU AP51079PU-N

Corticotropin Releasing Factor Receptor 2 (CRHR2) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.; Western blot: 1/100 - 1/500.; Immunohistochemistry on paraffin sections: 1/50 - 1/100.; Flow Cytometry: 1/10 - 1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 10-39 amino acids from human CRHR2
• Specificity: This antibody reacts to CRFR2.
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 47688 Da
• Gene Name: corticotropin releasing hormone receptor 2
• Database Link:
  Q13324
• Background: Liaw et al. (1996) [PubMed 8536644] stated that there are 2 G protein-coupled corticotropin-releasing hormone (CRH; MIM 122560) receptors, CRHR1 (MIM 122561) and CRHR2, which they termed the CRF2 receptor. CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge.
• Synonyms: Corticotropin-releasing factor receptor 2, CRF-R 2, CRF2, CRF2R, CRH2R

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction