CPN1 (Center) Rabbit Polyclonal Antibody

SKU AP51053PU-N

CPN1 (Center) rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/50-1/100.; Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 209-240 amino acids from the Central region of Human CPN1.
• Specificity: This antibody recognizes Human CPN1 (Center).
• Buffer: PBS; State: Purified; State: Liquid purified Ig fraction; Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: carboxypeptidase N subunit 1
• Database Link:
  P15169
• Background:
  ;

  Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq].

  ;
• Synonyms: CPN, CPN1, ACBP, Kininase-1, Serum carboxypeptidase N, Anaphylatoxin inactivator, Plasma carboxypeptidase B, Lysine carboxypeptidase, Arginine carboxypeptidase, SCPN
• Note: Molecular Weight: 52286 Da

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein