CHD1L (Center) Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100 - 1/500. |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 560-590 amino acids from the Central region of human CHD1L |
Specificity | This antibody reacts to CHD1L. |
Buffer | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 78kd Isoform 3. 100984 Da |
Gene Name | chromodomain helicase DNA binding protein 1 like |
Database Link | |
Background | In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]). [supplied by OMIM]. |
Synonyms | ALC1 |
Reference Data |
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