GBA (C-term) Rabbit Polyclonal Antibody

SKU AP46301PU-N

GBA (C-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution:

  Western blotting (0.2 - 1 µg/ml)

• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide directed towards the C-term region of human Glucosylceramidase
• Buffer: State: Aff - Purified; State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.; Note that this product is shipped as lyophilized powder to China customers.
• Purification: Purified using peptide immunoaffinity column
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: glucosylceramidase beta
• Database Link:
  NP_000148
  P04062
• Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
• Synonyms: Beta-glucocerebrosidase, Alglucerase, Imiglucerase, GBA, GC, GLUC, Acid beta-glucosidase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism