thrb Goat Polyclonal Antibody

SKU AP33293PU-N

thrb goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, WB
• Recommended Dilution: Peptide ELISA: 1/32000 (Detection Limit).; Western blot: 2-5 µg/ml. Approx 50kDa band observed in Zebrafish adult Heart lysates (calculated MW of 44.3kDa according to NP_571415.1).
• Reactivity: Zebrafish
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_571415.1.
• Specificity: This antibody recognizes Thrb (Zebrafish) and is not expected to cross-react to THRA.
• Buffer: Tris saline, pH~7.3; State: Aff - Purified; State: Liquid purified Ig fraction; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: thyroid hormone receptor beta
• Database Link:
  Q9PVE4
• Background: Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TRalpha and TRBeta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3-triiodo-L-thyronine (T-3).
• Synonyms: Thyroid hormone receptor beta, THR1, NR1A2

Reference Data