Melatonin Receptor 1B (MTNR1B) Goat Polyclonal Antibody

SKU AP31974PU-N

Melatonin Receptor 1B (MTNR1B) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC
• Recommended Dilution:

  Peptide ELISA: 1/32000 (Detection limit). ; Western blot: Preliminary experiments gave approx .48kDa and 37kDa bands in Human Brain (Cerebellum) lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 40.2kDa according to NP_005950.1. The 48kDa and 37kDa bands were successfully blocked by incubation with the immunizing peptide. ; We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported? ; Immunohistochemistry on Paraffin Sections: 3-6 μg/ml. In paraffin embedded Cerebellum shows membranous staining primarily in Purkinje cells.

• Reactivity: Human
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide with sequence from the C Terminus of Human MTNR1B (NP_005950.1).
• Specificity: This antibody detects MTNR1B at C-term
• Buffer: Tris saline, pH~7.3; State: Aff - Purified; State: Liquid purified Ig fraction; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: melatonin receptor 1B
• Database Link:
  P49286
• Background: MTNR1b is a Melatonin Receptor that mediates the effects of melatonin in the retina and the photoperiodic control of neuroendocrine functions. It may also be involved in melatonin-induced immune enhancement.MTNR1b has been reported in adipose, brain, eye, and ovary. An EST has been isolated from an eye tissue library.
• Synonyms: MTNR1B

Reference Data