Dopamine beta Hydroxylase (DBH) (437-448) Goat Polyclonal Antibody

SKU AP31950PU-N

Dopamine beta Hydroxylase (DBH) (437-448) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, WB
• Recommended Dilution:
  Peptide ELISA: 1/128000 (Detection limit). ; Western blot: 1-3 µg/ml. Detects band of Approx 70kDa in lysates of cell line Jurkat.; Primary incubation was 1 hour. Preliminary testing was unsuccessful on Mouse and Rat Brain for this particular batch.;
  Immunohistochemistry on Paraffin Sections: 5 µg/ml in Paraffin embedded Human Adrenal Gland.
• Reactivity: Bovine, Human, Mouse, Porcine, Rat
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide (-DNHYSPHFQEIR) from the internal region of Human DBH (NP_000778.3).
• Specificity: This antibody recognizes DBH (437-448). ; This batch is not expected to cross-react with Mouse and Rat in Western blot.
• Buffer: Tris saline, pH~7.3; State: Aff - Purified; State: Liquid purified Ig fraction; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: dopamine beta-hydroxylase
• Database Link:
  P09172
• Background: DBH is a member of the copper type II, ascorbate-dependent monooxygenase family, which catalyzes the conversion of dopamine to norepinephrine, a key neurotransmitter in the central and peripheral nervous systems. The effects of DBH plasma levels have been a focus area for both neurological and psychiatric disorders, including Parkinsons disease, hypertension, depression, schizophrenia, drug abuse and stress.
• Synonyms: DBH, Dopamine beta-monooxygenase, DBM, DOPO

Reference Data