VG5Q (AGGF1) Rabbit Polyclonal Antibody

SKU AP26397PU-N

VG5Q (AGGF1) rabbit polyclonal antibody, Purified

Product Data

• Application: ELISA, IHC, IP, WB
• Recommended Dilution: Immunohistochemistry on frozen sections.; Immunohistochemistry on paraffin sections.; Immunoassays.; Immunoprecipitation.; Western blot.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: VG5Q functions as an angiogenic factor in promoting angiogenesis and suppression of VG5Q expression inhibits vessel formation. Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. Angiogenesis has an essential role in pathological conditions such as cancer and various ischaemic and inflammatory diseases.; VG5Q can bind to endothelial cells and promote cell proliferation, suggesting that the protein may act in an autocrine fashion. VG5Q interacts with TWEAK (also known as TNFSF12), another secreted angiogenic factor.; VG5Q shows strong expression in blood vessels and is secreted when vessel formation is initiated. VG5Q protein was detected mostly in the cytoplasm and around the nuclei of human microvascular endothelial cells (HMVECs). Furthermore VG5Q is detected in human umbilical vein endothelial cells (HUVECs), human heart fibroblast (HHF) and ovarian cancer cells (OV-3), but low expression was detected in kidney cancer cells (RP-45), HeLa Cells and bladder cancer cells.
• Specificity:
  The antibody reacts with human VG5Q, a 84 kDa protein.
• Buffer: PBS; State: Purified; State: Liquid 0.2 µm filtered Ig fraction; Stabilizer: 0.1% bovine serum albumin; Preservative: 0.02% sodium azide
• Concentration: lot specific
• Purification: Protein A
• Conjugation: Unconjugated
• Storage:

  Store at 2 - 8 °C.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: angiogenic factor with G-patch and FHA domains 1
• Database Link:
  Q8N302
• Synonyms: GPATC7, GPATCH7

Reference Data