Col7a1 (NC1 FN-III-like Dom 7+8) Rabbit Polyclonal Antibody

SKU AP23438PU-N

Col7a1 (NC1 FN-III-like Dom 7+8) rabbit polyclonal antibody, Purified

Product Data

• Application: ELISA, IF, IHC
• Recommended Dilution: ELISA.; Immunofluorescence.; Immunohistochemistry on Cryosections (Ref.3); Induction of Experiemental EBA in Mice (Ref.2,3).
• Reactivity: Mouse
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant Murine Collagen type VII (aa 757-967) GST fusion protein.
• Specificity: This antibody recognizes Murine 290 kDa type VII Collagen (epidermal basement membrane / anchoring fibril component).
• Buffer: Matrix: IgG; Protein A purified from serum; PBS pH 7.2, 20 mM D-(+)-trehalose dihydrate, 40 mM D-(-)-mannitol; State: Purified; State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore in aqua bidest to 1 mg/ml.
• Purification: Protein G Chromatography
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.; After reconstitution store the antibody undiluted (in aliquots) at -20°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient
• Gene Name: collagen, type VII, alpha 1
• Database Link:
  Q63870
• Background: Type VII collagen fibrils are composed of three identical alpha collagen chains. It's location is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in the collagen V11 gene are associated with all forms of dystrophic epidermolysis bullosa.
• Synonyms: COL7A1, Long-chain collagen, LC collagen

Reference Data