VRL1 (TRPV2) (595-764) Rabbit Polyclonal Antibody

SKU AP23163PU-N

VRL1 (TRPV2) (595-764) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.; Western Blot: 1/500 - 1/3000.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 595 and 764 of VRL1
• Specificity: This antibody detects TRPV2 / Vanilloid receptor-like protein 1 at aa 595-764.
• Buffer: 0.1 M Tris-glycine, pH 7, 10% Glycerol containing 0.01% Thimerosal as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody in aliquots at -20°C. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: transient receptor potential cation channel subfamily V member 2
• Database Link:
  Q9Y5S1
• Background: Transient Receptor Potential Vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.
• Synonyms: VRL, OTRPC2, Vanilloid receptor-like protein 1, VRL-1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane