GRIA4 (279-292) Goat Polyclonal Antibody

SKU
AP22578PU-N
GRIA4 (279-292) goat polyclonal antibody, Aff - Purified
$595.00
3 Weeks*
Specifications
Product Data
Application ELISA, IHC, WB
Recommended Dilution ELISA: 1/128000, 0.3 - 1 µg/ml.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 0.3 - 1 µg/ml.
Reactivity Bat, Bovine, Canine, Chicken, Equine, Human, Monkey, Mouse, Rabbit, Rat
Antibody Host Goat
Clonality Polyclonal
Immunogen Peptide with from the internal region of the protein sequence according to NP_000820.3, NP_001070711.1, NP_001070712.1
Specificity This antibody detects Glutamate receptor 4 / GLUR4 (Internal).
It is expected to recognize all reported isforms (NP_000820.3; NP_001070711.1; NP_001070712.1). Reported variants NP_001070712.1 and NP_001106283.1 represent identical protein.
Buffer Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Immunoaffinity chromatography
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name glutamate ionotropic receptor AMPA type subunit 4
Database Link
Background Human glutamate receptor 4 (GRIA4) is a new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Binding studies showed that human GRIA4 transfected into simian kidney cells (COS-1) exhibits high specific binding for[3H](RS)-alpha-amino- 3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) but not [3H]kainate. Ion substitution experiments indicate that hGluR4 receptor-linked ion channels in their homomeric state are permeable to both CA2+ and Na+ ions. Immunoprecipitation studies suggest that GRIA1 exists in situ in the form of a pentamer.
Synonyms GluR-4, GRIA4, GluR-D, GluA4, Glutamate receptor ionotropic AMPA4
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.