KMT2B (2703-2715) Goat Polyclonal Antibody

SKU AP22567PU-N

KMT2B (2703-2715) goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC
• Recommended Dilution: ELISA: 1/128000.; Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivity: Bovine, Human, Monkey, Mouse, Porcine, Rat, Zebrafish
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-term of human MLL4
• Specificity: This antibody detects MLL4 (C-term).
• Buffer: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: lysine methyltransferase 2B
• Database Link:
  Q9UMN6
• Background: This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.
• Synonyms: WBP7, HRX2, KIAA0304, KMT2D, MLL2, TRX2

Reference Data

• Protein Families: Druggable Genome