PSMA4 Goat Polyclonal Antibody

SKU AP21301PU-N

PSMA4 goat polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, WB
• Recommended Dilution: Peptide ELISA: 1/4000 (Detection Limit).; Western blot: 0.3-1 µg/ml. This antibody detects a band of ~28kDa in lysates of cell line K562, NIH3T3 and in lysates of Human Tonsil, Human Peripheral Blood Mononucleocytes and in Mouse and Rat Spleen.
• Reactivity: Canine, Human, Mouse, Rat
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002780.1 and NP_001096138.1
• Specificity: This antibody is expected to recognize both reported isoforms (NP_002780.1 and NP_001096138.1).
• Buffer: Tris saline, pH~7.3; State: Aff - Purified; State: Liquid purified IgG fraction; Stabilizer: 0.5% BSA; Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: proteasome subunit alpha 4
• Database Link:
  P25789
• Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA4 is a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: Proteasome subunit alpha type-4, Macropain subunit C9, Proteasome component C9, HC9, PSC9, Proteasome subunit L
• Note: Calculated Molecular Weight: 29.5kDa (NP_002780.1)

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Proteasome