c-Myb (MYB) Rabbit Polyclonal Antibody

SKU AP21138PU-N

c-Myb (MYB) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.; Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 491-540 of Human c-Myb.
• Specificity: This antibody detects endogenous levels of c-Myb protein.; (region surrounding Ile526)
• Buffer: Phosphate buffered saline (PBS), pH 7.2; State: Aff - Purified; State: Liquid purified Ig fraction (> 95% (by SDS-PAGE); Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: ~ 80 kDa
• Gene Name: MYB proto-oncogene, transcription factor
• Database Link:
  P10242
• Background: c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc. c-Myb is expressed predominantly in immature and rapidly dividing hematopoietic cells, and cellular levels of c-Myb substantially decreases as cells reach terminal differentiation. B-Myb is expressed in a wide variety of proliferating cells, with levels accumulating during the G1 to S phase transition. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes.
• Synonyms: c-Myb

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transcription Factors