IKB beta (NFKBIB) Rabbit Polyclonal Antibody

SKU AP21089PU-N

IKB beta (NFKBIB) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of IkappaB-beta protein.; (region surrounding Ala13)
• Buffer: Phosphate buffered saline (PBS), pH 7.2; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: ~ 37 kDa
• Gene Name: NFKB inhibitor beta
• Database Link:
  Q15653
• Background: Three major forms of IkappaB-like molecules have been identified and each is characterized by multiple copies of ankyrin repeats. IkappaB-alpha and IkappaB-beta appear to be the major regulatory forms of IkappaB in most cells. These proteins interact with p65 or c-Rel containing forms of NFkappaB and block nuclear import by masking the nuclear localization sequences of NFkappaB. The activation of NFkB involves the inducible phosphorylation and subsequent degradation of IkappaB. Immunoblotting easily detects the hyper-phosphorylated forms of IkappaB-alpha, but not phosphorylated IkappaB-beta.
• Synonyms: I-kappa-B-beta, TRIP9, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9

Reference Data

• Protein Families: Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Adipocytokine signaling pathway, B cell receptor signaling pathway, Chemokine signaling pathway, Cytosolic DNA-sensing pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway