KCNMA1 Rabbit Polyclonal Antibody

SKU AP20653PU-N

KCNMA1 rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.; Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 750-800 of Human MaxiKα
• Specificity: This antibody detects endogenous levels of MaxiKα protein.; (region surrounding Gln770)
• Buffer: Phosphate buffered saline (PBS), pH 7.2; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: ~ 137 kDa
• Gene Name: potassium calcium-activated channel subfamily M alpha 1
• Database Link:
  Q12791
• Background: MaxiK channels are large conductance, voltage and calciumsensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the poreforming alpha subunit and the modulatory beta subunit. KCNMB2 is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents.
• Synonyms: Maxi K, BK, K VCA, BKCA channel, Slowpoke homolog, Slo-alpha, Slo1, hSlo

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Protein Pathways: Vascular smooth muscle contraction