Oct-1 (POU2F1) Rabbit Polyclonal Antibody
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | Western blot: 1/500-1/1000. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Specificity | This antibody detects endogenous levels of Oct-1 protein. |
| Buffer | Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | 1.0 mg/ml |
| Purification | Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 89 kDa |
| Gene Name | POU class 2 homeobox 1 |
| Database Link | |
| Background | Oct1 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR and interacts with NR3C1, AR and PGR. Oct1 is Ubiquitous and belongs to the POU transcription factor family class 2 subfamily. Oct1 contains 1 homeobox domain. |
| Synonyms | OTF1, NF-A1, Octamer-binding protein 1, Oct-1, Otf-1 |
| Reference Data | |
| Protein Families | Druggable Genome, Transcription Factors |
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