ZWINT (Center) Rabbit Polyclonal Antibody

SKU AP17856PU-N

ZWINT (Center) rabbit polyclonal antibody, Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.; Western blotting: 1/1000.; Flow Cytometry: 1/10-1/50.; Immunohistochemistry: 1/50-1/100.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 59-88 selected from the Center region of Human ZWINT
• Specificity: This antibody recognizes ZW10 interactor/ZWINT (Center).
• Buffer: PBS; State: Purified; State: Liquid purified Ig fraction.; Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: ZW10 interacting kinetochore protein
• Database Link:
  O95229
• Background: ZWINT is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells.
• Synonyms: Zwint-1
• Note: Calculated MW: 31293 Da

Reference Data

• Protein Families: Druggable Genome