IFNGR2 (C-term) Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry on paraffin sections. |
Reactivity | Human |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide selected from the C-terminal region of human IFNGR2 |
Specificity | This antibody reacts to IFNGR2. |
Buffer | PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | interferon gamma receptor 2 (interferon gamma transducer 1) |
Database Link | |
Background | IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. |
Synonyms | IFN-gamma receptor 2, IFN-gamma-R2, Interferon-gamma receptor beta, AF1 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity |
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