CYP2R1 (C-term) Rabbit Polyclonal Antibody

SKU AP14746PU-N

CYP2R1 (C-term) rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.; Western blotting: 1/50 - 1/100.; Immunohistochemistry: 1/50 - 1/100.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CYP2R1.
• Specificity: This antibody reacts to CYP2R1.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Purified; State: Liquid purified Ig
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: cytochrome P450 family 2 subfamily R member 1
• Database Link:
  Q6VVX0
• Background: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
• Synonyms: Vitamin D 25-hydroxylase, Cytochrome P450 2R1

Reference Data