Pumilio 1 (PUM1) (62-91) Rabbit Polyclonal Antibody

SKU AP14217PU-N

Pumilio 1 (PUM1) (62-91) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Peptide ELISA: 1/1,000.; Western blotting: 1/1,000.; Immunohistochemistry: 1/10-1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y83 (aa 62-91) of human PUM1.
• Specificity: This antibody recognizes PUM1.
• Buffer: PBS with 0.09% (W/V) sodium azide; State: Aff - Purified; State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: pumilio RNA binding family member 1
• Database Link:
  Q14671
• Background: PUM1 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.
• Synonyms: Pumilio homolog 1, HsPUM, Pumilio-1, PUMH1, KIAA0099

Reference Data