TIE2 (TEK) pTyr1113 Rabbit Polyclonal Antibody

SKU AP12973PU-N

TIE2 (TEK) pTyr1113 rabbit polyclonal antibody, Aff - Purified

Product Data

• Recommended Dilution: ELISA: 1/1,000.; Dot Blot: 1/500.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK.
• Specificity: This antibody detects TEK pTyr1113.; Predicted to cross react with Mouse and Zebrafish (100% Antigen Homology).
• Buffer: PBS with 0.09% (W/V) Sodium Azide as preservative.; State: Aff - Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: TEK receptor tyrosine kinase
• Database Link:
  Q02763
• Background: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
• Synonyms: TIE2, TIE-2, Angiopoietin-1 receptor, p140 TEK
• Note: Molecular weight: 125810 Da

Reference Data