MET pTyr1356 Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | ELISA: 1/1,000. Western Blot: 1/100-1/500. |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with 4=4 branches MAPS conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1356 of human MET. |
Specificity | This antibody detects HGF Receptor (MET) pTyr1356. |
Buffer | PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | MET proto-oncogene, receptor tyrosine kinase |
Database Link | |
Background | The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. |
Synonyms | Hepatocyte growth factor receptor, MET, Scatter factor receptor, HGF/SF receptor, c-Met |
Note | Molecular weight: 155527 Da |
Reference Data |
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