CBX8 (C-term) Rabbit Polyclonal Antibody

SKU AP12236PU-N

CBX8 (C-term) rabbit polyclonal antibody, Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.; Western Blot: 1/100-1/500.; Immunohistochemistry: 1/50-1/100.
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CBX8.
• Specificity: This antibody is specific to CBX8 (C-term).
• Buffer: PBS with 0.09% (W/V) Sodium Azide as preservative.; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: chromobox 8
• Database Link:
  Q9HC52
• Background: Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.
• Synonyms: Chromobox protein homolog 8, Polycomb 3 homolog, Rectachrome 1, PC3, RC1
• Note: Predicted Molecular weight: 43437 Da

Reference Data