VIP Guinea Pig Polyclonal Antibody
Product Data | |
Application | IF, IHC |
---|---|
Recommended Dilution | Immunofluorescence: 1/1000-1/2000 with overnight incubation at 2-8°C. Immunohistochemistry on Frozen and Paraffin Sections. Recommended Positive Control: Stefanini-fixed frozen sections of rat intestine. |
Reactivity | Feline, Guinea Pig, Human, Porcine, Rabbit, Rat |
Antibody Host | Guinea Pig |
Clonality | Polyclonal |
Immunogen | Synthetic Human VIP (Peninsula, #7161). |
Specificity | Antibody AP09566SU-N recognizes VIP (Vasoactive intestinal peptide). Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining, while PHI does not. |
Buffer | State: Serum State: Lyophilized undiluted serum containing 0.09% sodium azide. |
Reconstitution Method | Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.1% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Gene Name | vasoactive intestinal peptide |
Database Link | |
Background | VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas. |
Synonyms | VIP, Vasoactive intestinal peptide |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
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