Cytokeratin 3 (KRT3) Guinea Pig Polyclonal Antibody
| Product Data | |
| Application | IF, IHC |
|---|---|
| Recommended Dilution | Immunofluorescence. Immunohistchemistry on Frozen Sections: 1/100-1/200. Incubation Time: 1h at RT. Positive Control: Human cornea. |
| Reactivity | Human, Mouse |
| Antibody Host | Guinea Pig |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of Human keratin K3 (formerly also designated cytokeratin 3; C- IKF SQS SQS SQR YSR), coupled to KLH |
| Specificity | MW 63,000 (pI 7.5) intermediate filament polypeptide, keratin K3, detected by Immunohistochemistry in the cornea only. Useful as a marker for corneal type differentiation (positive for epithelial cells of cornea) and for studying corneal epithelial stem cells. |
| Buffer | State: Serum State: Liquid Serum Preservative: 0.09% Sodium Azide, 0.5% BSA |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | keratin 3 |
| Database Link | |
| Background | Cytokeratin 3 belongs to the intermediate filament family. It is a type II cytokeratin and is specifically expressed in the corneal epithelium. Cytokeratin 3 associates with Cytokeratin 12. Defects in Cytokeratin 3 are a cause of Meesmann corneal dystrophy. |
| Synonyms | Keartin-3, KRT3, Type-II keratin Kb3 |
| Reference Data | |
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