ENPP1 (915-925) Goat Polyclonal Antibody
Product Data | |
Application | ELISA, IHC |
---|---|
Recommended Dilution | ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 2.5 - 5 µg/ml. |
Reactivity | Human, Mouse, Rabbit, Rat |
Antibody Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from C-terminus of Human ENPP1, aa 915-925 (NP_006199.2) |
Specificity | Specific to Human ENPP1 (C-term). |
Buffer | Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Immunoaffinity Chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
Database Link | |
Background | ENPP1 has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. It can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. |
Synonyms | ENPP-1, M6S1, NPPS, PC1, PDNP1, E-NPP 1 |
Reference Data |
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