Oxytocin Receptor (OXTR) (C-term Cytopl. Dom.) Rabbit Polyclonal Antibody

SKU AP06927PU-N

Oxytocin Receptor (OXTR) (C-term Cytopl. Dom.) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: ELISA, IHC
• Recommended Dilution: ELISA.; Immunohistochemistry on Paraffin Sections: 40 µg/ml.
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic 19 amino acid peptide from C-terminal cytoplasmic domain of human Oxytocin Receptor
• Specificity: This antibody detects Oxytocin Receptor (OXTR), C-terminal cytoplasmic domain.
• Buffer: Phosphate buffered saline containing 0.09% Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: oxytocin receptor
• Database Link:
  P30559
• Background: The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.
• Synonyms: OT-R

Reference Data